It is important to carefully collect these data, as different projects address different types of tissue damage and the related scientific data may be important for histopathological evaluation and reporting. type of tissue, experimental setting, and genetic background).

Scientific data are related to each specimen (i.e. The second german research center (Sonderforschungsbereich 832: 'Molecular basis and modulation of cellular interactions in the tumour microenvironment') aims to determine key mechanisms that cause and affect the interaction between cancer cells and their microenvironment.

The mission of our first german transregional research center (Sonderforschungsbereich/Transregio 57: 'Organ fibrosis: From mechanisms of injury to modulation of disease') is to identify principles of liver and kidney fibrosis and to develop new strategies to inhibit organ fibrosis or induce its regression. In our setting different research groups from two transregional research centers submit hundreds of animal and pseudonymized research tissue samples per year to our histopathological core facility for examination. Central image storage can be accessed by the workgroups. It will also analyse and quantitate pathological changes. The histopathological platform will embed the specimen and perform histopathological and immunohistochemical staining using a standardized set of antibodies. The different research laboratories provide tissue samples and enter related data in the database. Work flow of the histopathological platform.

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